Angioimmunoblastic lymphadenopathy with paraproteinemia: A T- and B-Cell disorder

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Abstract
A case is reported of angioimmunoblastic lymphadenopathy (AILD), in which a IgM Kappa monoclonal gammopathy developed. On the first admission the immunoblasts were shown to be T cells by surface-marker studies. Although the number of circulating T cells was normal, their functional capacities were markedly reduced. The patient was followed for two months at the end of which she died with hematologic features of immunoblastic plasma cell leukemia.