Induction of Convulsive Seizures in Sound Sensitive Albino Mice: Response to Various Signal Frequencies
- 1 September 1972
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 140 (4) , 1284-1288
- https://doi.org/10.3181/00379727-140-36659
Abstract
Summary Convulsive seizures were induced in audiosensitive seizure-prone mice, O'Grady strain, with defined sound signals. Optimum frequency for seizure induction was 13 kHz, but a signal of 22 kHz, inaudible to human observers, was also satisfactory. Measurements with an octave band filter covering the main mouse hearing range established that no one wavelength was specifically responsible for seizure induction: all frequencies between 8-30 kHz were convulsive, depending only on the mouse hearing acuity.Keywords
This publication has 0 references indexed in Scilit: