Effect of treatment on Campylobacter pylori in peptic disease: a randomised prospective trial.
Open Access
- 1 March 1988
- Vol. 29 (3) , 279-283
- https://doi.org/10.1136/gut.29.3.279
Abstract
This study investigated the effect of colloidal bismuth subcitrate and cimetidine on Campylobacter pylori in peptic disease. In 74% of 135 patients with peptic disease diagnosed at endoscopy C pylori was detected before treatment. Compared with cimetidine, colloidal bismuth subcitrate significantly decreased the incidence of C pylori after six weeks of treatment (p less than 0.001). In the colloidal bismuth subcitrate group, subsequent healing of the lesion was correlated with the clearance of C pylori, unlike in the cimetidine group. C pylori was strongly associated with the presence of histological gastritis, which was decreased by colloidal bismuth subcitrate (p less than 0.001).This publication has 24 references indexed in Scilit:
- Interaction of tripotassium dicitrato bismuthate with macrophages in the rat and in vitroGastroenterology, 1986
- Surface morphology of the gastroduodenal mucosa in duodenal ulceration.Gut, 1984
- Campylobacter like organisms on the gastric mucosa: culture, histological, and serological studies.Journal of Clinical Pathology, 1984
- UNIDENTIFIED CURVED BACILLI IN THE STOMACH OF PATIENTS WITH GASTRITIS AND PEPTIC ULCERATIONThe Lancet, 1984
- Spiral organisms in endoscopic biopsies of the human stomach.Journal of Clinical Pathology, 1984
- Unidentified curved bacilli on gastric epithelium in active chronic gastritis.1983
- DIFFERENCE IN RELAPSE RATES OF DUODENAL ULCER AFTER HEALING WITH CIMETIDINE OR TRIPOTASSIUM DICITRATO BISMUTHATEThe Lancet, 1981
- Randomised open controlled trial of colloidal bismuth subcitrate tablets and cimetidine in the treatment of duodenal ulcer.Gut, 1980
- Tri-potassium Di-citrato BismuthateDrugs, 1976
- The antrum in patients with duodenal and gastric ulcers.Gut, 1967