Prostaglandins and pruritus*
- 1 March 1976
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 94 (3) , 273-275
- https://doi.org/10.1111/j.1365-2133.1976.tb04383.x
Abstract
We have found that pretreatment of human skin with prostaglandin E1 significantly lowers the threshold of human skin to itching evoked by both histamine and papain. Prostaglandins may thus potentiate pruritus in inflammatory skin disease, presumably by a non-specific effect on nerve-endings.Keywords
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