Abstract
The subepicardial injection of 0.1 cc of digitalis or of a strophanthin preparation, as well as of other substances, over the sinus area leads to the immediate but transient appearance of sinoauricular block. This phenomenon is attributed to a reflex inhibition of the sinus node centers caused by the mechanical stimulus and not to a specific effect of the injected substances. In some instances the centers of the auriculo-ventricular node are also inhibited.
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