The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling

This publication has 59 references indexed in Scilit:

• Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity
  Molecular and Cellular Biology, 2004
• EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
  Science, 2004
• Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
  Nature Cell Biology, 2003
• Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
  Nature Cell Biology, 2003
• The Tyrosine Phosphatase PRL-1 Localizes to the Endoplasmic Reticulum and the Mitotic Spindle and Is Required for Normal Mitosis
  Journal of Biological Chemistry, 2002
• Regulation of TSC2 by 14-3-3 Binding
  Published by Elsevier ,2002
• Farnesyltransferase Inhibitor Induces Rapid Growth Arrest and Blocks p70s6k Activation by Multiple Stimuli
  Published by Elsevier ,2000
• Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas
  Oncogene, 1998
• Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase
  Nature Genetics, 1998
• A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb
  FEBS Letters, 1995