GROWTH AND REPRODUCTIVE RATES OF MICE

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Abstract
Crosses were made among segments of a mouse population which had been selected for small, medium, and large size with both inbred and outbred groups in each size. Inbreeding of the inbreds averaged 15 and 30 percent at the time of the first and second series of crosses, respectively. Sixty-day weights of the progeny of crosses between size groups in all cases were near-the average of the two parental types, thus indicating a preponderantly additive or multiplicative type of inheritance with little evidence of heterosis. In the second series of crosses, mice sired by inbred males were significantly heavier than those sired by outbreds. Both sires and dams of litters influenced the number of young per litter. Females resulting from the second series of crosses were bred, sacrificed late in pregnancy and numbers of embryonic sites counted. Average embryo numbers in females resulting from the crosses between size groups in all cases were close to or slightly above the averages of the two parental types.

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