Measles Virus Infection of Mouse Neuroblastoma (C 1300) Cells
- 1 October 1980
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 165 (1) , 55-62
- https://doi.org/10.3181/00379727-165-40933
Abstract
C 1300 mouse neuroblastoma cells were permissively infected with measles virus. No cytopathic changes were observed in light microscopy although yields of infective virus comparable to those of infected Vero [African green monkey kidney] cells were demonstrable. Persistently infected measles virus carrier cell lines were established. The growth rate of these cells was reduced and they exhibited a higher degree of morphological differentiation than uninfected neuroblastoma cells. Infected cells demonstrated hemagglutinin and hemolysin activities on the cell surface. EM revealed accumulation of viral nucleocapsids in the cytoplasm but no viral components in the nuclei. In association with the measles virus infection, a marked reduction of acetylcholinesterase activity of C 1300 cells was detected.This publication has 3 references indexed in Scilit:
- Growth of measles virus in continuous cell lines derived from the nervous tissues of human and ratArchiv für die gesamte Virusforschung, 1979
- Replication of Measles Virus in a Cell Culture from a Glioblastoma of Human OriginJournal of Neuropathology and Experimental Neurology, 1977
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951