Effects of Thiouracil on the Mammary Gland.
- 1 June 1945
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 59 (2) , 197-200
- https://doi.org/10.3181/00379727-59-15031
Abstract
Thiouracil administered to normal or castrated male and female rats failed to induce an alteration of the mammary glands similar to that obtained following thyroidectomy. The mammary glands of rats treated with thiouracil and with estrogen for the last 10 days of the experimental period possessed well developed lobules and alveoli whereas the control glands showed end bud growth and duct extension. When thyroxin was given along with thiouracil and estrogen, the mammary glands resembled those from rats receiving estrogen alone and no precocious lobule-alveolar growth was noted.Keywords
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