Receptor binding specificity of recent human H3N2 influenza viruses
Open Access
- 9 May 2007
- journal article
- Published by Springer Nature in Virology Journal
- Vol. 4 (1) , 42
- https://doi.org/10.1186/1743-422x-4-42
Abstract
Human influenza viruses are known to bind to sialic acid linked α2-6 to galactose, but the binding specificity beyond that linkage has not been systematically examined. H3N2 human influenza isolates lost binding to chicken red cells in the 1990s but viruses isolated since 2003 have re-acquired the ability to agglutinate chicken erythrocytes. We have investigated specificity of binding, changes in hemagglutinin sequence of the recent viruses and the role of sialic acid in productive infection.Keywords
This publication has 58 references indexed in Scilit:
- Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptorsNature, 2006
- Design of carbohydrate multiarraysBiochimica et Biophysica Acta (BBA) - General Subjects, 2006
- Glycan Microarray Analysis of the Hemagglutinins from Modern and Pandemic Influenza Viruses Reveals Different Receptor SpecificitiesJournal of Molecular Biology, 2005
- Amount and avidity of serum antibodies against native glycoproteins and denatured virus after repeated influenza whole-virus vaccinationVaccine, 2005
- Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza virusesGlycobiology, 2002
- Antibody Epitopes on the Neuraminidase of a Recent H3N2 Influenza Virus (A/Memphis/31/98)Journal of Virology, 2002
- Substitution of amino acid residue in influenza A virus hemagglutinin affects recognition of sialyl‐oligosaccharides containing N‐glycolylneuraminic acidFEBS Letters, 1999
- Expression of Functional Influenza Virus A Polymerase Proteins and Template from Cloned cDNAs in Recombinant Vaccinia Virus Infected CellsBiochemical and Biophysical Research Communications, 1994
- Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificityVirus Research, 1993
- Comparison of hemagglutination and hemadsorption tests for influenza detectionDiagnostic Microbiology and Infectious Disease, 1992