Internal hydrocephalus, optic nerve aplasia, and microphthalmia in CPB-WE (Wezob) and Cpb: WU (Wistar) rats
Open Access
- 1 July 1986
- journal article
- research article
- Published by SAGE Publications in Laboratory Animals
- Vol. 20 (3) , 257-265
- https://doi.org/10.1258/002367786780865548
Abstract
Wistar rats of the inbred CPB-WE and the random bred Cpb:WU strains have been used in neuro-anatomical studies. In both groups of rats a high incidence of hydrocephalus was observed. In the CPB-WE rats the ventricular dilatation was accompanied by optic tract lesions and microphthalmia. The present report describes the gross and microscopic findings in these rats and discusses the possible aetiology.Keywords
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