Rapid Microwave-Assisted Solid Phase Peptide Synthesis
- 23 August 2002
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2002 (11) , 1592-1596
- https://doi.org/10.1055/s-2002-33348
Abstract
A microwave-assisted, rapid solid phase peptide synthesis procedure is presented. It has been applied to the coupling of sterically hindered Fmoc-protected amino acids yielding di- and tripeptides. Optimized conditions for a variety of coupling reagents are reported. Peptides were obtained rapidly (1.5-20 min) and without racemization.Keywords
This publication has 0 references indexed in Scilit: