Cadmium metabolism in cdm/cdm mice
- 1 August 1979
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 17 (7-8) , 731-736
- https://doi.org/10.1007/bf00502131
Abstract
The uptake and metabolism of cadmium by cadmium-susceptible (+/+) and cadmium-resistant (cdm/cdm) strains of mice have been compared. These strains did not differ with respect to the quantitative uptake of cadmium into liver, kidney, or testis. After intraperitoneal administration of a nontoxic dose, more than 80% of the cadmium in liver and testis of both strains is bound to low molecular weight proteins. The chromatographic behavior of these cadmium-binding proteins is not affected by cdm genotype.This publication has 14 references indexed in Scilit:
- Mouse liver metallothioneins. Purification, molecular weight, amino acid composition, and metal content.Journal of Biological Chemistry, 1978
- Association of cadmium with renal cancerCancer, 1976
- Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content.1974
- Genetic Analysis of Resistance to Cadmium-Induced Testicular Damage in MiceExperimental Biology and Medicine, 1973
- Isolation of cadmium-binding proteinsCellular and Molecular Life Sciences, 1971
- Distribution of Cadmium Among Protein Fractions of Mouse Liver1)Acta Pharmacologica et Toxicologica, 1971
- Distribution of Cadmium 109 and Zinc 65 in Mice of Inbred StrainsArchives of environmental health, 1969
- SENSITIVITY OF MAMMALS TO CADMIUM NECROSIS OF THE TESTISReproduction, 1965
- STRAIN DIFFERENCES IN SUSCEPTIBILITY OF MICE AND RATS TO CADMIUM-INDUCED TESTICULAR DAMAGEReproduction, 1965
- Observations on the early events of cadmium necrosis of the testisThe Anatomical Record, 1964