Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A
- 15 December 2006
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 16 (24) , 6306-6309
- https://doi.org/10.1016/j.bmcl.2006.09.012
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic ApplicationsPhysiological Reviews, 2006
- The Synthetic Triterpenoids, CDDO and CDDO-Imidazolide, Are Potent Inducers of Heme Oxygenase-1 and Nrf2/ARE SignalingCancer Research, 2005
- Betulinic acid-induced apoptosis in leukemia cellsLeukemia, 2004
- A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide productionBioorganic & Medicinal Chemistry Letters, 2002
- Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cellsCancer Letters, 2001
- Synthetic Oleanane and Ursane Triterpenoids with Modified Rings A and C: A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse MacrophagesJournal of Medicinal Chemistry, 2000
- Novel Synthetic Oleanane and Ursane Triterpenoids with Various Enone Functionalities in Ring A as Inhibitors of Nitric Oxide Production in Mouse MacrophagesJournal of Medicinal Chemistry, 2000
- Betulinic acid induces apoptosis in human neuroblastoma cell linesEuropean Journal Of Cancer, 1997
- Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosisNature Medicine, 1995