The new cell culture smallpox vaccine should be offered to the general population
- 1 January 2002
- journal article
- review article
- Published by Wiley in Reviews in Medical Virology
- Vol. 13 (1) , 5-15
- https://doi.org/10.1002/rmv.382
Abstract
A series of major factors must be weighed in deciding whether or not, and to what extent, a particular country should consider pre-exposure vaccination for smallpox. These include the risk of a bioterrorist attack using smallpox, the risk of secondary spread from another country, the risks and benefits of vaccination, the effectivenes s of vaccination pre- and post-exposure, the prevalence of immunocompromised persons, the capacity of the medical care delivery system and the wealth of a nation. We review here the issues and variables relevant for policy making, propose a framework for country-specific decision making and suggest the World Health Organization has a key role to play, particularly with regard to lower-income countries. In doing so, we support the proposition.Keywords
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