Structural and biochemical analysis of Ras‐effector signaling via RalGDS
Open Access
- 21 May 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 451 (2) , 175-180
- https://doi.org/10.1016/s0014-5793(99)00555-4
Abstract
The structure of the complex of Ras with the Ras‐binding domain of its effector RalGDS (RGS‐RBD), the first genuine Ras‐effector complex, has been solved by X‐ray crystallography. As with the Rap‐Raf...Keywords
This publication has 32 references indexed in Scilit:
- Three-dimensional structure of the Ras-interacting domain of RalGDSNature Structural & Molecular Biology, 1997
- Cloning and evaluation of RALGDS as a candidate for the tuberous sclerosis gene TSC1Annals of Human Genetics, 1997
- Identification of a Novel RalGDS-related Protein as a Candidate Effector for Ras and Rap1Published by Elsevier ,1996
- Molecular Studies of CtpA, the Carboxyl-terminal Processing Protease for the D1 Protein of the Photosystem II Reaction Center in Higher PlantsJournal of Biological Chemistry, 1996
- Interactions between Ras proteins and their effectorsCurrent Opinion in Biotechnology, 1996
- Ras/Rap effector specificity determined by charge reversalNature Structural & Molecular Biology, 1996
- Differential Interaction of the Ras Family GTP-binding Proteins H-Ras, Rap1A, and R-Ras with the Putative Effector Molecules Raf Kinase and Ral-Guanine Nucleotide Exchange FactorPublished by Elsevier ,1996
- Stimulation of Membrane Ruffling and MAP Kinase Activation by Distinct Effectors of RASScience, 1996
- The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogueNature, 1995
- The CCP4 suite: programs for protein crystallographyActa Crystallographica Section D-Biological Crystallography, 1994