Level of C-Reactive Protein as a Measure of Acute Myocardial Infarction.

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Abstract
The C-reactive protein probably is an abnormal constituent of human serum, an alpha globulin. It is formed by the body in response to inflammation. Its detection in human serum by specific rabbit antiserum has served as a sensitive but nonspecific test for inflammation of rheumatic activity. C-reactive protein was detected in the serum of 7 consecutive patients with acute myocardial infarction and in 1 patient with acute coronary insufficiency and myocardial necrosis. Sera of 6 patients with coronary insufficiency but without myocardial necrosis were negative for C-reactive protein. These preliminary observations suggest that the test may be a sensitive indicator of myocardial necrosis and inflammation.

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