Treating viral hepatitis C: efficacy, side effects, and complications
Top Cited Papers
- 1 September 2006
- Vol. 55 (9) , 1350-1359
- https://doi.org/10.1136/gut.2005.076646
Abstract
The treatment of hepatitis C has dramatically improved over the past decade. Unlike any other chronic viral infection, a significant proportion of patients with chronic hepatitis C can be cured. However, the current standard therapy--pegylated interferon alpha and ribavirin--has its limitations. Limited efficacy in patients with hepatitis C virus (HCV) genotype 1 and the side effect profile will necessitate the development of new therapeutic approaches. This review describes the efficacy and optimisation of the current standard therapy of hepatitis C and its problems in special patient populations. New treatment directions beyond interferon alpha based therapies are on the horizon.Keywords
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