Systemic sclerosis, morphoea and breast cancer

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Abstract
Sir, systemic sclerosis (SSc) and localized scleroderma (LS) are generally considered to be different entities. Raynaud's phenomenon, sclerodactyly, internal organ involvement and scleroderma-specific autoantibodies are usually not observed in LS. Nevertheless, there have been occasional reports of SSc and LS occurring together or LS evolving into SSc [1], suggesting a link between these disorders. We therefore describe a woman with SSc who developed typical lesions of generalized morphoea. A year later, invasive ductal carcinoma of breast was diagnosed. We discuss the rare coexistence of systemic sclerosis and morphoea, and the possible implications of breast cancer.