Clinical Features of Chlamydia trachomatis Rectal Infection by Serovar Among Homosexually Active Men

Publisher Website
Google Scholar
Abstract
BecauseC. trachomatisserovars correlate with the clinical manifestations of cervical infection, we undertook this study to determine whether clinical, behavioral, and laboratory findings correlate withC. trachomatisserovars isolated from rectal infections. To correlateC. trachomatisserovar with signs and symptoms of rectal infection. A cross-sectional study of 454 men with rectalC. trachomatisinfection attending an urban sexually transmitted disease (STD) clinic was undertaken. Isolates were thawed, passaged to high titer, and typed using a panel of monoclonal antibodies. Compared to men infected with B complex isolates (164), men with C complex isolates (55) were less likely to report symptoms (OR: 0.4; 95% CI: 0.1-0.8), or to have erythema, bleeding, or mucopus (OR: 0.3; 95% CI: 0.1-0.8). Among men with inclusion counts of more than 100, those infected with FG group versus B complex isolates were more likely to present with mucopus (OR: 10.5; 95% CI: 1.2-95.5), more than 15 polymorphonuclear leukocytes (OR: 19.2; 95% CI: 1.7-219.8), and proctitis (OR: 4.2; 95% CI: 1.1-16.7). Signs and symptoms of rectal infection correlate with the serovar ofC. trachomatisisolates.