RADIATION‐INDUCED PARATHYROID ADENOMAS AND THYROID TUMORS IN RATS
- 1 March 1981
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section A Pathology
- Vol. 89A (1-6) , 425-429
- https://doi.org/10.1111/j.1699-0463.1981.tb00241.x
Abstract
Parathyroid morphology was studied in 45 irradiated and 37 control rats. The irradiated rats received a single parathyroid dose of about 6.5 gray. The rats were killed and autopsied 14 mo. later. The radiation resulted in fibrosis and depression in weight of the parathyroids. In irradiated rats, 11 parathyroid adenomas and 4 thyroid tumors were found. In control rats, no tumor occurred in either parathyroid or thyroid glands. All irradiated rats, including those with a parathyroid adenoma, were normocalcemic.Keywords
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