Lack of association between bipolar affective disorder and tyrosine hydroxylase DNA marker
- 15 July 1993
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 48 (2) , 87-89
- https://doi.org/10.1002/ajmg.1320480206
Abstract
Sixty-eight patients with bipolar affective disorder and 88 controls were investigated for genetic association of tyrosine hydroxylase (TH) restriction fragment length polymorphisms (RFLPs). No significant association between bipolar affective disorder and TH was found. Thus the hypothesis that TH is involved in the pathogenesis of bipolar affective disorder was not supported.Keywords
This publication has 18 references indexed in Scilit:
- Tyrosine hydroxylase polymorphisms and bipolar affective disorderJournal of Psychiatric Research, 1991
- Linkage analysis of manic depression in an Irish family using H-ras 1 and INS DNA markers.Journal of Medical Genetics, 1988
- Genetic linkage between X-chromosome markers and bipolar affective illnessNature, 1987
- Bipolar affective disorders linked to DNA markers on chromosome 11Nature, 1987
- Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigreesNature, 1987
- A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control ProbandsArchives of General Psychiatry, 1982
- Age‐of‐onset and genetic transmission in affective disordersActa Psychiatrica Scandinavica, 1981
- The inheritance of affective disorders: A review of data and of hypothesesBehavior Genetics, 1976
- Norepinephrine in Depressive ReactionsArchives of General Psychiatry, 1965
- THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCEAmerican Journal of Psychiatry, 1965