The D-State

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Abstract
Pharmacology and the D-StateA great many data, mostly from small informal studies, are available concerning the effect of drugs on the D-state, but as yet no definite pattern has emerged. A number of substances decrease the amount of time spent in the D-state. This is true in man for phenobarbital and several other barbiturates studied so far.20 Phenothiazines likewise tend to decrease D-time; trifluoperazine (Stelazine) has some confusing early effects54 but probably actually decreases D-time like the others.55 Alcohol has been shown to cause a decrease in D-time,56 and in fact it has been suggested that delirium tremens may . . .