Leukopenia — A New Immune Mechanism?

Publisher Website
Google Scholar
Abstract
The mechanisms involved in producing a clinical state of leukopenia with recurrent infection in man have been difficult to elucidate clearly. Certain drugs and other environmental factors can produce total marrow aplasia or selective absence of marrow leukocyte precursors, with resultant production deficit and leukopenia that is frequently of lethal severity. However, more often, patients have reduced leukocytes in the presence of marrow precursors, and ability to define the pathophysiologic process has been hindered by a variety of problems unique to the granulocyte, including cumbersome radioactive-labeling technics, tendency to clumping and other artifactual lesions, short circulation time (four to 12 . . .

This publication has 2 references indexed in Scilit: