Benzotetramisole: A Remarkably Enantioselective Acyl Transfer Catalyst
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- 1 March 2006
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (7) , 1351-1354
- https://doi.org/10.1021/ol060065s
Abstract
A commercially available pharmaceutical, tetramisole, was found to be a competent enantioselective acylation catalyst. Its benzannellated analogue, benzotetramisole (BTM), produced outstanding enantioselectivities in kinetic resolution of secondary benzylic alcohols.Keywords
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