Studies on the Antibacterial Action of Spermine
- 1 February 1954
- journal article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 10 (1) , 11-16
- https://doi.org/10.1099/00221287-10-1-11
Abstract
SUMMARY: Spermine was found to inhibit the growth of various micro-organisms. The most susceptible were Staphylococcus aureus and Staph. albus, Neisseria gonorrhoeae and N. meningitidis, and to a lesser degree Bacillus anthracis. The Enterobacteriaceae were relatively resistant. The action of spermine was enhanced by an increase in pH of the medium. The antibacterial effect was bactericidal; it was slowed but not prevented by a decrease in temperature from 37 to 6°. The nutrients of various media influenced the action of spermine.Keywords
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