[51Cr]EDTA Intestinal Permeability in Children with Cowʼs Milk Intolerance

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Abstract
Making use of [51Cr]EDTA as a permeability marker, we measured intestinal permeability in a group of 20 children with proven cow''s milk intolerance (CMI), a group of 17 children with similar complaints where CMI wwas excluded (sick controls), and a group of 12 control children. [P51Cr]EDTA test results (mean .+-. SD) were 6.85 .+-. 3.64%, 3.42 .+-. 0.94%, and 2.61 .+-. 0.67% in the group with CMI, the sick control, and the control group, respectively. When compared to both control groups, patients with cow''s milk intolerance (CMI) showed a significantly increased small bowel permeability. We conclude that the [51Cr]EDTA test can be helpful for the diagnosis of cow''s milk intolerance.