TheStreptomyces coelicolorPolynucleotide PhosphorylaseHomologue, and Not the Putative Poly(A) Polymerase, CanPolyadenylateRNA
Open Access
- 15 December 2003
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (24) , 7273-7278
- https://doi.org/10.1128/jb.185.24.7273-7278.2003
Abstract
A protein containing a nucleotidyltransferase motif characteristic of poly(A) polymerases has been proposed to polyadenylate RNA inStreptomyces coelicolor(P. Bralley and G. H. Jones, Mol. Microbiol.40:1155-1164, 2001). We show that this protein lacks poly(A) polymerase activity and is instead a tRNA nucleotidyltransferase that repairs CCA ends of tRNAs. In contrast, aStreptomyces coelicolorpolynucleotide phosphorylase homologue that exhibits polyadenylation activity may account for the poly(A) tails found in this organism.Keywords
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