Über die Sauerstoffaufnahme von Schnitten experimentell verfetteter Lebern
- 1 January 1953
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 295 (Jahresband) , 77-83
- https://doi.org/10.1515/bchm2.1953.295.1.77
Abstract
Fatty livers were induced in rats and mice by a high fat, low-protein diet. The respiration of liver slices from such animals was 45-70% lower than that of slices from normal animals. Addition of succinate restored the respiration of fatty liver slices to normal, but fumarate, malate, aspartate, glutamate, glucose and pyruvate had no effect. The block is suggested to lie in the diphosphopyridine nucleotide (DPN)-enzyme sequence. There was no difference in the respiration of diaphragm slices from normal and experimental animals.Keywords
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