N2-Isobutyryl-O6-[2-(p-Nitrophenyl)Ethyl]Guanine: A New Building Block for the Efficient Synthesis of Carbocyclic Guanosine Analogs
- 1 July 1992
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 11 (6) , 1257-1261
- https://doi.org/10.1080/07328319208018340
Abstract
N2-Isobutyryl-O6-[2-(p-nitrophenyl)ethyl]guanine (4) allows the synthesis of different types of carbocyclic analogs of guanosine in high yield under Mitsunobu conditions. Only the desired N9-substituted derivatives of guanine are formed.Keywords
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