The MSS51 gene product is required for the translation of the COX1 mRNA in yeast mitochondria
- 1 October 1990
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 224 (1) , 111-118
- https://doi.org/10.1007/bf00259457
Abstract
The MSS51 gene product has been previously shown to be involved in the splicing of the mitochondrial pre-mRNA of cytochrome oxidase subunit I (COX1). We show here that it is specifically required for the translation of the COX1 mRNA. Furthermore, the paromomycin-resistance mutation (P inf454 supR ) which affects the 15 S mitoribosomal RNA, interferes, directly or indirectly, with the action of the MSS51 gene product. Possible roles of the MSS51 protein on the excision of COX1 introns are discussed.Keywords
This publication has 28 references indexed in Scilit:
- Nucleo‐mitochondrial interactions in yeast mitochondrial biogenesisEuropean Journal of Biochemistry, 1989
- The functional role of ribosomal RNA in protein synthesisCell, 1989
- Nuclear gene products required for translation of specific mitochondrially coded mRNAs in yeastTrends in Genetics, 1986
- The primary structure of the mitochondrial genome of Saccharomyces cerevisiae — a reviewGene, 1986
- An mRNA maturase is encoded by the first intron of the mitochondrial gene for the subunit I of cytochrome oxidase in S. cerevisiaeCell, 1983
- Analysis of a yeast nuclear gene involved in the maturation of mitochondrial pre-messenger RNA of the cytochrome oxidase subunit ICell, 1983
- Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 geneGene, 1979
- [14] Yeast petite mutants for DNA gene amplificationPublished by Elsevier ,1979
- [6] Analysis of products of mitochondrial protein synthesis in yeast: Genetic and biochemical aspectsPublished by Elsevier ,1979
- A mutant of Saccharomyces cerevisiae defective for nuclear fusion.Proceedings of the National Academy of Sciences, 1976