Thin Layer Chromatographic Analysis of Basic and Quaternary Drugs Extracted as Bis(2-ethylexyl)phosphate Ion-Pairs
- 1 December 1987
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography & Related Technologies
- Vol. 10 (16) , 3595-3604
- https://doi.org/10.1080/01483918708077816
Abstract
Thin layer chromatography in the normal and reversed phase mode is evaluated as a qualitative analysis method for various basic and quaternary drugs extracted as bis(2-ethylhexyl)phosphate ion-pairs. A combination of two thin layer chromatographic systems, a reversed phase system and a fairly apolar normal phase system, is shown to cover the analysis of drugs with different grades of polarity. Based on that, a method for screening of urine samples for drugs is described.This publication has 0 references indexed in Scilit: