Farnesyl Pyrophosphate Synthetase Located in Microsomes from Pig Liver1
- 1 June 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 93 (6) , 1635-1639
- https://doi.org/10.1093/oxfordjournals.jbchem.a134302
Abstract
The microsomes from pig liver contained farnesyl pyrophosphate synthetase and it was solubilized with Triton X-100. The microsomal enzyme had a pH optimum of 6.5–7.0 and required Mg 2+ or Mn 2+ for maximum activity. Dimethylallyl-transferring activity of the enzyme was much lower compared with the geranyl-transferring activity. In the presence of Triton X-100, the geranyl-transferring activity was about two-fold activated whereas the dimethylallyl-transferring activity was almost the same.Keywords
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