Fragilitas ossium: a new autosomal recessive mutation in the mouse

Publisher Website
Google Scholar
Abstract
Fragilitas ossium, fro, is an often lethal recessive mutation that was discovered in a randombred stock of mice after treatment with the chemical mutagen tris(i-aziridinyl) phosphine-sulphine. The frolfro mice have osteoporosis—bending and fracture of the long bones—that is associated with apparently normal cartilage growth. The roentgenological and pathological features are similar to those of the severe, often lethal recessive form of human osteogenesis imperfecta.

This publication has 2 references indexed in Scilit: