Structure and stereochemistry of brianolide, a new antiinflammatory diterpenoid from the Okinawan gorgonianBriareum sp.

Abstract
Brianolide (1), a new antiinflammatory diterpenoid of the briarein class, possessing a β substituent at C-12 (R), has been isolated from the Okinawan gorgonianBriareum sp. Its structure has been established from spectral data in conjunction with a single crystal X-ray analysis.