Use of a Compaction Simulator System in Tabletting Research

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Abstract
The components and principal operating features of a compaction simulator system are described. Initial experiments with 8 model materials, using single-ended and double-ended compression waveforms are reported. Data obtained at two tablet machine speeds (30 and 150rpm) and at two compressional pressure levels (80 and 400MPa) demonstrate a correlation between total work or average power consumed during the process and the tensile strength of the tablets. Non-linearity of Heckel plots and limited compliance with the Walker equation are also shown.