Medical and surgical therapies for keloids
Top Cited Papers
- 1 June 2004
- journal article
- review article
- Published by Hindawi Limited in Dermatologic Therapy
- Vol. 17 (2) , 212-218
- https://doi.org/10.1111/j.1396-0296.2004.04022.x
Abstract
Keloids are benign, but sometimes painful and/or pruritic, proliferative growths of dermal collagen, usually resulting from excessive tissue response to trauma. Although benign, the social and psychological impact on affected individuals must be considered. Keloids often arise secondary to ear piercing and operative procedures. No single treatment modality is always successful. The more common ones are discussed. Some of the medical therapies include corticosteroids, interferon, 5-fluorouracil, and imiquimod. Primary excision and cryosurgery are among the major surgical options. Radiation therapies and other physical modalities are also discussed.Keywords
This publication has 20 references indexed in Scilit:
- Pilot study of the effect of postoperative imiquimod 5% cream on the recurrence rate of excised keloidsJournal of the American Academy of Dermatology, 2002
- Are keloids really “gli-loids”?: High-level expression of gli-1 oncogene in keloidsJournal of the American Academy of Dermatology, 2001
- Treatment of Inflamed Hypertrophic Scars Using Intralesional 5-FUDermatologic Surgery, 1999
- Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alfa-2b injectionsJournal of the American Academy of Dermatology, 1997
- Treatment of Earlobe Keloids with Surgery Plus Adjuvant Intralesional Verapamil and Pressure EarringsAnnals of Plastic Surgery, 1996
- Selective inhibition of human diploid fibroblast collagen synthesis by interferons.Journal of Clinical Investigation, 1984
- Treatment of Keloids and Hypertrophic Scars with Adhesive Zinc TapeScandinavian Journal of Plastic and Reconstructive Surgery, 1982
- Pharmacologic Control of Surface Scarring in Human BeingsAnnals of Surgery, 1981
- The local treatment of hypertrophic scars and keloids with topical retinoic acidBritish Journal of Dermatology, 1980
- In Vitro Inhibition of Cell Growth, Collagen Synthesis, and Prolyl Hydroxylase Activity by Triamcinolone AcetonideExperimental Biology and Medicine, 1980