Immunochemistry of the Proteins of Dog Hair

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Abstract
Summary and Conclusions: From dog hair there can be dissolved out with weak alkali a small amount of protein. Part of this, the “alkali metaprotein,” can be precipitated by neutralization while the rest remains dissolved but can be recovered from solution by dialysing out the salt and evaporating to dryness. This we have called “dog hair peptone.”. These two proteins show themselves, by their skin reactions with asthmatics, to be immunologically distinct and also distinct from a peptone obtained from pure keratin, which is itself inactive, by hydrolysis, and from the serum proteins of the same species.

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