A Definitive Role of RhoC in Metastasis of Orthotopic Lung Cancer in Mice

Open Access

1 February 2004

journal article
Published by American Association for Cancer Research (AACR) in Clinical Cancer Research

Vol. 10 (3) , 1192-1200
https://doi.org/10.1158/1078-0432.ccr-03-0275

Abstract

Purpose: Lung cancer is a major cause of cancer death, and its incidence is increasing in the world. Conventional therapies remain less effective for metastases of lung cancer, leading to poor prognosis of this disorder. The present study investigates pathological roles of RhoC in metastasis of lung cancer using a clinically relevant mouse model of lung cancer.

Keywords

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