PRE-MORBID FACTORS IN HODGKINS-DISEASE .2. BCG-VACCINATION STATUS, TUBERCULOSIS, INFECTIOUS-DISEASES, TONSILLECTOMY, AND APPENDECTOMY

  • 1 January 1978
    • journal article
    • research article
    • Vol. 21  (4) , 273-277
Abstract
In young adults with Hodgkin''s disease [HD], cell mediated immunity (CMI) was evaluated retrospectively from their health records. The register of records from the school health service of the Copenhagen Council was scrutinized to find the records of those with HD born between 1930-1950 in whom the disease had been diagnosed between 1943-1975. Whenever possible, 3 controls were selected from the register for each case. They were comparable in respect of sex, year and month of birth and socio-economic background. The material consisted of 63 cases and 182 controls. Information regarding BCG-vaccinations, tuberculin skin-tests, the frequency of tuberculosis, bacterial and viral diseases, and of tonsilectomy, adenoidectomy and appendectomy was obtained from the school health records. Two HD patients have had tuberculosis while none did in the control group. Complications or prolonged course of viral diseases were not reported in HD patients or in controls. No significant differences were found in the frequency of BCG-vaccination, tuberculin reactivity, viral and bacterial diseases, adenoidectomy, tonsilectomy and appendectomy. The concept of a pre-morbid CMI deficiency state in HD was not supported.

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