IMMUNOREACTIVE CALCITONIN IN AMYLOID FIBRILS OF MEDULLARY CARCINOMA OF THE THYROID-GLAND - AN IMMUNOGOLD STAINING TECHNIQUE

  • 1 July 1986
    • journal article
    • research article
    • Vol. 110  (7) , 647-649
Abstract
A lymph node containing metastatic medullary carcinoma of the thyroid gland was examined immunohistochemically for the presence of calcitonin by light and electron microscopy. Electron microscopy showed dense, selective labeling of the tumor-associated amyloid fibrils and labeling of the scanty intracytoplasmic neurosecretory granules. By light microscopy, a few tumor cells showed strong staining, whereas the amyloid fibrils showed equivocal staining.

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