Abstract
1. Human and guinea-pig sperms are susceptible to the most diverse chemicals to almost the same degree. 2. There exists a substance in human semen which protects both human and guinea-pig sperms against certain chemicals, especially sodium oleate, orthovanillin and potassium borotartrate. 3. When perfectly fresh human semen is not available, the spermicidal powers of substances may be tested by using guinea-pig sperms suspended in human semen which has been kept cool.

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