The Cardiac Infarction Injury Score as a predictor for long-term mortality in survivors of a myocardial infarction

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Abstract
Aims The Cardiac Infarction Injury Score (CIIS) is an electrocardiographic classification system that was developed as a diagnostic tool to assess the extent of cardiac injury in acute myocardial infarction. We investigated the prognostic value of the CIIS in post-myocardial infarction patients. Methods and Results The prognostic values of the CIIS for total and cardiac mortality was assessed in a large series (n=3395) of patients who were enrolled in the ASPECT trial. Standard 12-lead electrocardiograms, recorded prior to hospital discharge were coded according to the CIIS and the Minnesota Code. Mean CIIS was 26 (range −8 to 59). After adjustment for other baseline characteristics, the CIIS was directly related to the risk of total mortality and cardiac mortality. At one-year follow-up the relative risks of CIIS ≥40, CIIS 30–40 and CIIS 20–30 were significantly higher than in those with a CIIS 40. Conclusion The CIIS ECG scoring system is an important predictor for long-term cardiac mortality in post myo-cardial infarction patients. It can easily be automated and is efficient for classifying cardiac injury in epidemiological studies.

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