Polymers carrying sLex‐mimetics are superior inhibitors of E‐selectin‐dependent leukocyte rolling in vivo
Open Access
- 3 November 2003
- journal article
- fj express-summarie
- Published by Wiley in The FASEB Journal
- Vol. 18 (1) , 152-154
- https://doi.org/10.1096/fj.03-0346fje
Abstract
Selectins mediate leukocyte rolling and may represent good anti-inflammatory drug targets. Detailed knowledge regarding the structure of selectin ligands has permitted development of selectin antagon...Keywords
Funding Information
- British Heart Foundation (FS/98051)
This publication has 38 references indexed in Scilit:
- Glycosulfopeptides modeled on P‐selectin glycoprotein ligand‐1 inhibit P‐selectin‐dependent leukocyte rolling in vivoThe FASEB Journal, 2002
- Control of leukocyte rolling velocity in TNF-α–induced inflammation by LFA-1 and Mac-1Blood, 2002
- Pharmacology of Selectin Inhibitors in Ischemia/Reperfusion StatesAnnual Review of Pharmacology and Toxicology, 2000
- Interactions of the Cytoplasmic Domain of P-Selectin with Clathrin-coated Pits Enhance Leukocyte Adhesion under FlowThe Journal of cell biology, 1998
- The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand BiosynthesisCell, 1996
- The alpha 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo.The Journal of Experimental Medicine, 1996
- P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.The Journal of cell biology, 1995
- Multivalent sialyl-LeX: potent inhibitors of E-selectin-mediated cell adhesion; reagent for staining activated endothelial cellsGlycobiology, 1994
- Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversityPublished by Elsevier ,1991
- The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140Cell, 1991