Direct Synthesis of Chiral Acetals from Carbonyl Compounds and Chiral Diols: Sequential One-Pot Asymmetric Silylcyanation Reaction Catalyzed by Scandium(III) Triflate

Abstract
Chiral acetal formation followed by cyanation of carbonyl compounds was successfully carried out in one-pot using chiral diols, scandium (III) triflate and then trimethylsilyl cyanide.

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