Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate.
Open Access
- 1 July 1988
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 51 (7) , 924-928
- https://doi.org/10.1136/jnnp.51.7.924
Abstract
A prospective, double-blind, placebo-controlled investigation of possible withdrawal symptoms from phenytoin, carbamazepine and sodium valproate is reported in patients with active epilepsy, on combination therapy. There was an increase in seizures on reduction and withdrawal of carbamazepine, but there was no convincing evidence of withdrawal symptoms from any of these drugs.Keywords
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