N-Isopropyl-p-123I-Amphetamine Single Photon Emission Computer Tomography in Motor Neuron Disease
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in European Neurology
- Vol. 29 (5) , 255-260
- https://doi.org/10.1159/000116422
Abstract
N-Isopropyl-p-123I-amphetamine (123I-IMP) single photon emission computer tomography studies were performed on 17 patients suffering from amyotrophic lateral sclerosis (ALS). All patients displayed varying degrees of impaired fixation of 123I-IMP in the whole brain. These findings were not related to the clinical variants of ALS and the age of the patients. A correlation between the severity of the disease and the degree of impaired fixation could be observed. In addition, patients suffering from ALS for longer periods showed more pronounced impairment of 123I-IMP fixation.Keywords
This publication has 12 references indexed in Scilit:
- Single photon emission computed tomography (SPECT) brain imaging using N,N,N′‐trimethyl‐N′‐(2 hydroxy‐3‐methyl‐5– 123 Iiodobenzyl)‐1,3‐propanediamine 2 HCl (HIPDM)Neurology, 1986
- Positron emission tomography in Alzheimer's diseaseNeurology, 1986
- Abnormal sensory evoked potentials in amyotrophic lateral sclerosisNeurology, 1986
- Cerebral blood flow studies using N-isopropyl I-123 p-iodoamphetamine.Stroke, 1985
- Cerebral Perfusion Imaging With Iodine 123-Labeled AminesArchives of Neurology, 1984
- Somatosensory evoked potentials in amyotrophic lateral sclerosis.Journal of Neurology, Neurosurgery & Psychiatry, 1984
- The Fluorodeoxyglucose 18F Scan in Alzheimer's Disease and Multi-infarct DementiaArchives of Neurology, 1983
- N-isopropyl(I-123)p-iodoamphetamine brain scans with single-photon emission tomography: discordance with transmission computed tomography.Radiology, 1982
- QUANTIFYING LOCAL CEREBRAL BLOOD-FLOW BY N-ISOPROPYL-P-(I-123)IODOAMPHETAMINE (IMP) TOMOGRAPHY1982
- Functional landscapes of the dominant hemisphereBrain Research, 1976