Study of the Effects of Diphenylhydantoin Sodium on the Lungs
- 30 March 1961
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 264 (13) , 648-651
- https://doi.org/10.1056/nejm196103302641306
Abstract
MERRITT and Putnam1 first reported the effectiveness of diphenylhydantoin sodium in the treatment of epilepsy in 1938. This drug is now widely used, and further experience has confirmed its great value in the control of epileptic seizures, especially major motor and psychomotor spells. A detailed discussion of the various untoward reactions that have been observed in association with diphenylhydantoin sodium therapy (in our clinic and also by other physicians) was presented by one of us in 1956.2 In 1959 Moore3 reported what he classified as a "toxic manifestation," not heretofore observed, caused by hydantoin drugs. He stated that 27 (87 . . .Keywords
This publication has 3 references indexed in Scilit:
- PULMONARY CHANGES IN HYDANTOIN THERAPYJAMA, 1959
- Treatment of Epilepsy With Diphenylhydantoin SodiumPostgraduate Medicine, 1956
- SODIUM DIPHENYL HYDANTOINATE IN THE TREATMENT OF CONVULSIVE DISORDERSJAMA, 1938