Localization of Cu/Zn-SOD and Mn-SOD in the Rat Cochlea

1 January 1996

journal article
research article
Published by Taylor & Francis in Acta Oto-Laryngologica

Vol. 116 (6) , 833-835
https://doi.org/10.3109/00016489609137935

Abstract

Distributions of the copper/zinc-superoxide dismutase (Cu/Zn-SOD) and the manganese superoxide dismutase (Mn-SOD) in the rat cochlea were studied by immunohistochemistry with specific polyclonal antibodies to Mn-SOD and Cu/Zn-SOD. Coexpression of Mn-SOD and Cu/Zn-SOD was observed in the cochlear tissues with differing immunoactivity intensities. The presence of Cu/Zn- and Mn-SOD implies the existence of a defense system against free oxygen radical (FOR) injury in cochlear tissues.

Keywords

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