Abstract
A tremendous amount of effort and large sums of money are being expended in many laboratories in attempts to discover new, active and useful antimicrobial agents. The intensive research and screening programs under way were designed particularly to discover substances active against infections that are not now adequately controlled by the agents currently available, or have equal or greater activity but lower toxicity or less sensitizing properties in human beings. For the manufacturers or commercial sponsors of a new and useful antibiotic, this means considerable prestige and, if the agent is active against a wide spectrum of infections or against . . .

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